Tom Maniatis, Ph.D.

Posted on March 12th, 2012

Tom Maniatis, Ph.D. Tom Maniatis is the Isidore S. Edelman Professor and chairman of the department of biochemistry and molecular biophysics at the Columbia University Medical Center. He received his B.S. and M.S. degrees from the University of Colorado at Boulder in chemistry and biology, and his Ph.D. in molecular biology from Vanderbilt University. After postdoctoral studies at Harvard University and the MRC Laboratory of Molecular Biology in Cambridge, England, Dr. Maniatis held faculty positions at Harvard University, the Cold Spring Harbor Laboratory and the California Institute of Technology.

Dr. Maniatis is known for pioneering the development of gene cloning technology and its application to basic research and biotechnology. His research has impacted a broad spectrum of biomedical fields, from basic mechanisms of gene regulation, to human genetic and inflammatory diseases. Dr. Maniatis’ laboratory is currently focused on molecular neuroscience, with interests in the role single cell diversity in the brain, and disease mechanisms in ALS.

Dr. Maniatis co-founded three biotechnology companies in the past 30 years, including Genetics Institute, which pioneered the development of FDA-approved recombinant therapeutic proteins, ProScript, where the small molecule cancer drug Velcade was invented, and Acceleron, which develops recombinant proteins for the treatment of musculoskeletal diseases. He is currently a member of the board of directors of Acceleron Pharma and Constellation Pharma, and is a science partner of The Column Group, a biotechnology venture firm.

Dr. Maniatis is a member of the Jackson Laboratory board of trustees, and has served on the board of rustees of the Cold Spring Harbor Laboratory. He currently serves on the Rockefeller University committee on scientific affairs and is a former member of the board of scientific consultants, Memorial Sloan-Kettering Cancer Center.  He is a co-founder of the New York Genome Center and sits on its executive committee. Dr. Maniatis is a member of the U.S. National Academy of Sciences.