Scientists at the HudsonAlpha Institute for Biotechnology have connected developmental delay and intellectual disability (DD/ID) to variations in the BRSK2 gene with the help of a social media platform used by geneticists all over the world.
A new HudsonAlpha project is just underway in collaboration with Crestwood ALS Care Clinic. In this project, HudsonAlpha scientists will conduct genomic sequencing and analysis of ALS patients to better understand the underlying cause of the disease. The project is funded through donations made to Impacting ALS, which is part of the M&M Program.
Rare disease patients spend an average of eight years searching for a diagnosis, and for some, that search can last decades. April Hudson began showing symptoms of an unknown disease at three years old. She would go on to see 200 physicians before finally learning the true cause of her symptoms nearly 40 years later.
HudsonAlpha internationally-renowned faculty members are committed to making impactful discoveries in genomics and genetics that improve health and create a more sustainable world.
Genomic and genetic analysis of human traits and diseases.
Richard Myers, PhD, is president and scientific director at HudsonAlpha. The Myers lab focuses on applying functional genomics and genetics approaches to understanding how genes and regulatory regions contribute to basic biology, human disease, responses to the environment and population genetics.
MD, George Washington University School of Medicine
Human clinical genetics
David Bick, MD, is a clinical geneticist with more than 20 years experience diagnosing and treating children with genetic disorders. Bick is the medical director of the Clinic for Genomic Medicine on the HudsonAlpha campus.
Epigenomic analysis of complex human traits and diseases
Devin Absher, PhD, uses the epigenome to study complex diseases and traits, especially autoimmune disease, cardiovascular disease, cancer and aging.
PhD in Genetics, Imperial College, London, UK
Clinical and translational use of genomic data
Liz Worthey, PhD, uses genomics and informatics to define the genetic underpinnings of human disease. In addition to her research goals, as the director of software development and informatics, she leads her team in supporting the informatics goals of the institute as well as the clinical mission to provide definitive diagnoses for patients.
Genetic architecture of morphologic variation
Greg Barsh, MD, PhD, studies the genetic mechanisms that underlie differences in individual appearance and that could give new insight into both basic biology and human disease.
Human Genetics and Genomics
Greg Cooper, PhD, researches the structures, functions and evolutionary histories of human genomes, with an emphasis on applying genomic approaches to study human disease.
Genomic resource development for plants
Jane Grimwood, PhD, co-directs the Genome Sequencing Center at HudsonAlpha, managing one of the few centers in the world that produces, analyzes and interprets genomic data on economically important plant and organism species to improve crop breeding and other agricultural practices.
Whole genome sequencing and assembly, population genomics
Jeremy Schmutz co-directs the Genome Sequencing Center at HudsonAlpha, managing one of the few centers in the world that produces, analyzes and interprets genomic data on economically important plant and organism species to improve crop breeding and other agricultural practices.
Technology development to advance medical science
Jian Han, MD, PhD, focuses on developing integrated solutions for molecular differential diagnosis and mapping the personalized immunorepertoire.
Understanding the role of the rhizome in resource reallocation and perenniality.
Kankshita Swaminathan, PhD, studies the role of the rhizome in nutrient storage and reproduction in plants. She is interested in how perennial plants remobilize nutrients year after year.
Educational outreach relating to genetics, genomics and biotechnology
Neil Lamb, PhD, oversees all educational programming developed at HudsonAlpha as vice president for educational outreach. Lamb creates innovative teacher training, student experiences, public enrichment, classroom kits and digital resources that re-shape how science education is delivered.
Sara Cooper, PhD, focuses on combining metabolomics with genomics and applying that data to pancreatic and ovarian cancer.
Technology development and automation, informatics, genomic variation
Shawn Levy, PhD, uses high performance genotyping and sequencing technologies to support projects from plant and animal phylogenetic studies to translational and clinical based projects at the Genomic Services Laboratory and the Clinical Services Laboratory.
Since opening its doors in 2008, HudsonAlpha has further secured its role as a global leader in biotechnology and genomic research. We’ve made discoveries in ALS, childhood genetic disorders and kidney cancer; expanded research in bipolar and schizophrenia and continued critical research in other devastating conditions, including cancer, Parkinson’s, lupus, multiple sclerosis and more.
Our agriscience team specializes in applying genomic techniques to understand how plants function in response to environmental stimuli. The HudsonAlpha Genome Sequencing Center is a global leader in providing de novo whole genome sequencing, assembly and analysis.
To leverage the synergy between discovery, education, medicine, and economic development in genomic sciences to improve the human condition around the globe.