HudsonAlpha investigator part of Department of Energy team focusing on tiny pest
WALNUT CREEK, Calif. and HUNTSVILLE, Ala. -- For a pest that isn't quite the size of a comma on a keyboard, the two-spotted spider mite can do a disproportionate amount of damage. These web-spinners extract the nutrients they need from leaves of more than a thousand different plant species, including bioenergy feedstocks and food staples. The cost of chemically controlling spider mites to counteract reduced harvest yields hovers around $1 billion annually, reflecting their significant economic impact.
Han lab turns out first patent for institute
HUNTSVILLE, Ala. -The HudsonAlpha Institute for Biotechnology has been awarded a patent for a new, rapid response method to detect pathogens from clinical samples. The method— amplicon rescue multiplex polymerase chain reaction for amplification of multiple targets— is highly sensitive and as the name implies, can differentiate between pathogens that symptomatically display very similarly among populations. It is the first patent awarded for institute-generated intellectual property.
Education partnership kicks up excitement in Alabama classrooms
HUNTSVILLE and MONTGOMERY Ala. - Lab coats, safety goggles, pipette tips, microwell plates, centrifuge tubes: Pretty standard issue for any biotech center or institute, right? But, 42,300 pairs of socks?
The National Institute of Mental Health has awarded the HudsonAlpha Institute for Biotechnology and the University of Michigan grant monies totaling $7.8 million to identify genes and pathways that contribute to the risk for bipolar disorder.
Study promotes improved diagnostics for severe pediatric disease
HUNTSVILLE, Ala - A study of almost 16,000 children with intellectual disability and various congenital defects is providing insight to more precise connections to anomalies in the genome. Greg Cooper, Ph.D., a faculty investigator at the HudsonAlpha Institute for Biotechnology, together with colleagues at the University of Washington in Seattle, and a dozen other organizations, identified 59 potentially pathogenic copy number variants and associated genes that appear to be linked to such disorders. The paper is currently available in the online version of Nature Genetics.
HUNTSVILLE, Ala - Research at the HudsonAlpha Institute for Biotechnology and Duke University, published in PLoS Genetics, uses genome-wide sequencing in families to demonstrate that the sequence of human DNA contributes much more to its own regulation than had been believed.
HudsonAlpha researchers demonstrate sporadic mutations may be responsible for half of schizophrenia cases
HUNTSVILLE, Ala. - Although it affects less than 1 percent of the global population, schizophrenia exacts a large toll in terms of expense and human suffering. A new study from researchers at the HudsonAlpha Institute for Biotechnology, with colleagues from Columbia University in New York and the University of Pretoria in South Africa, indicate non-familial genetic mutations may account for about half of schizophrenia cases.
HudsonAlpha Institute contributes to largest cancer genome study from NIH consortium
HUNTSVILLE, Ala - Integrating 500 patient samples and multiple genomic technologies, The Cancer Genome Atlas Research Network has, according to a release by the National Institutes of Health, assembled the most comprehensive view of cancer genes for any cancer type to date. The analyses of data are reported in the June 30 issue of Nature.
NIH program funds creative, innovative initiatives
HUNTSVILLE, Ala. - Educators at the HudsonAlpha Institute for Biotechnology have been awarded a grant in excess of $1.13 million to prompt Alabama students to make connections between the science classroom and the real world. “The grant, made possible through the National Institutes of Health, supports an initiative we’ve designed to help high school students identify genetic and environmental risks for human disease and then explore preventive measures based on that knowledge,” said Dr. Neil Lamb, director of educational outreach at HudsonAlpha.