Genome Sequencing Center

Dr. GrimwoodJane Grimwood, Ph.D. (read bio)
Faculty Investigator





Jeremy SchmutzJeremy Schmutz (read bio)
Faculty Investigator


Research interests

  • Genome improvement and finishing of eukaryotic organisms
  • Cloning systems
  • Host/pathogen interactions at the cellular and the genomic levels
  • Comparative sequence analysis
  • Whole genome sequencing and assembly
  • Constructing complex data collection and analysis systems in order to answer specific scientific questions
  • Genomic changes in populations in response to selective environmental pressures
  • Understanding the structural organization of genomes through comparative analysis of the genomes of related species

Information for the scientific community can be found by going to the personal webpage HudsonAlpha Genome Sequencing Center. 


Jeremy Schmutz receives cotton biotechnology award

News Outlet: 
PR Newswire
Date published: 
January 16, 2013

NEW YORK, Jan. 17, 2013 -- As part of the recent Plant and Animal Genomic Conference held in San Diego, Calif., Dr. Don Jones of Cotton Incorporated presented the 2012 Cotton Biotechnology Award to five outstanding researchers that were instrumental in mapping the cotton genome. The diverse and talented team, composed of Dr. Andrew Paterson, Dr. Jonathan Wendel, Mr. Jeremy Schmutz, Dr. Dan Peterson and Dr. Dan Rokhsar, led the collaborative international effort to complete the first "gold standard" Gossypium genome sequence.  

Study illuminates photosynthesis as an evolutionary process

HudsonAlpha scientists among those examining tiny algae

HUNTSVILLE, Ala - When you think about walking through a tall meadow of grass, you likely envision peace and calm. But on a sunny day those grass blades are busy factories turning light into food energy through a complex mechanism of enzymes arranged in the photosynthetic pathway. Those grass cells can only act as factories because distant ancestors declared war on other cells and swallowed them whole, trapping and forcing them to work for the grass cell.

Buttoning up the button mushroom genome


HUNTSVILLE, Ala - You may know it as your favorite pizza topping but researchers also know the button mushroom, or Agaricus bisporus, as a known decayer of leaves and other matter along the forest floor. Through an international collaboration including the HudsonAlpha Institute, the U.S. Department of Energy Joint Genome Institute and numerous other research labs, the full genome and gene repertoire for the button mushroom has been completed, giving scientists a better understanding of its full capabilities. 

Why we have plenty of fish in the sea

HUNTSVILLE, Ala. -- New work from the HudsonAlpha Institute for Biotechnology, with collaborators at Stanford University and five other groups, has pinpointed evolution in action.
By determining genomic sequence from many groups of stickleback fish, the scientists were able to show specific genomic changes leading to the ability of different fish populations to adapt to new environments. “We were pleased with the ability of genomics to show us what molecular changes are important in evolutionary processes,” said Richard Myers, Ph.D., president and director of HudsonAlpha. 

Spiraling in on animal development

In recent years scientists have determined the genome sequence of many animals, but many gaps still exist in the animal evolutionary tree. Headway was recently made, however, and three branches representing spiralian animals have now been sequenced. HudsonAlpha faculty investigator Jane Grimwood, Ph.D., contributed to the multi-institute study that spirals in on animal evolution. The study is published in the journal Nature.

Mushroom history could advance energy future

HUNTSVILLE, Ala.-- Fossil evidence suggests that coal deposits in the earth sharply decreased around the end of the Carboniferous period. Using genome sequence of fungi living now, Jeremy Schmutz from the HudsonAlpha Institute for Biotechnology and colleagues around the world say mushrooms may hold the clues to this decrease while also providing insight to spur technical progress for cellulosic biofuels production.

HudsonAlpha Genome Sequencing Center analyzes model grass species

Genome sequence and analysis advance sustainable food, feed and fuel resources

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Stickleback fish article published in Sciencexpress

The stickleback fish is an ideal organism for studying evolution in action, because there are many natural populations around the world and they display much variability in their features.  Researchers at HudsonAlpha have participated in an international collaboration to look for changes in DNA sequences which result in new or altered body features in the threespine stickleback fish.

What's all the fuzz about?

hermit crabHow can the fuzz that grows on the shells of hermit crabs have any relationship to human health? Well, the HudsonAlpha Genome Sequencing Center recently generated the finished genomic sequence for research conducted by Yale scientists studying Hydractinia symbiolongicarpus (the distinctive white fuzz growing on the top of hermit crab shells). The Yale scientists subsequently identified a candidate allorecognition gene that could eventually lead to better understanding of the human immune system. Allorecognition is the ability of an individual organism to distinguish its own tissues from those of another.

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