Dr. Martin Walsh of the Icahn School of Medicine at Mount Sinai (ISMMS) gave a presentation for the HudsonAlpha Research Seminars on Wednesday, November 30, in the HudsonAlpha auditorium.
Walsh is an Associate Professor of Pharmacological Sciences, Pediatrics Hepatology, and Genetics and Genomic Sciences at ISMMS. His research has been directed to investigate mechanisms in chromatin biology and protein biochemistry that directly influence gene transcription in different biological models that have included models of cystic fibrosis, cancer and stem cell biology. He has focused on understanding the molecular basis of disease and published over ninety peer-reviewed articles. Much of Walsh’s recent studies are linked with cystic fibrosis and are cancer-related through his focus on cellular senescence and the role transcriptional and chromatin regulators play in executing a senescence phenotype. Currently he is interested in RNA modification pathways leading to the control of self renewal and pluripotency in embryonic and cancer stem cell programming. He is recently engaged in understanding the role of long intervening non-coding RNAs (lincRNAs) and non-coding RNAs (ncRNAs) in the nuclear distribution of transcriptional and chromatin bound complexes at the molecular level in the progression toward malignant cell growth.
The next seminar will be Wednesday, December 7, featuring Dr. Steve Rowe of the University of Alabama at Birmingham.
More information on HudsonAlpha Research Seminars can be found at hudsonalpha.org/seminars.
